This thesis project aims to develop a computational fluid dynamics (CFD) model for the combustion analysis of a heavy duty hydrogen-fueled engine. Hydrogen is a very interesting alternative to fossil fuels, the most important disadvantages of which are its limited availability and pollutant emissions. Hydrogen, on the other hand, is very attractive thanks to its combustion product, which is water vapor, making it very sustainable. Among the several commercial CFD codes on the market, CONVERGE has been used for this study. This innovative software's most interesting quality is the time saving for mesh creation, which is automatically generated and refined locally.