Higher education plays a crucial role in addressing the demands of the modern knowledge economy and tackling complex societal challenges. These challenges, often referred to as “wicked problems,” require insights and expertise from multiple disciplines. Not only for addressing these challenges but also for enriching the processes of knowledge creation and innovation, fostering interdisciplinary collaboration within the institutions is essential. Architectural design can significantly contribute to facilitating the exchange of ideas and knowledge among people working on diverse disciplines within higher education campuses. This thesis will investigate how interdisciplinary collaboration can be encouraged in technical universities through spatial design. The objective is to design a project for a portion of the main engineering campus of Politecnico di Torino that proposes a hypothesis for redesigning the academic spatial environment to encourage interdisciplinary collaboration.