As it is well known, the attention to sustainable mobility has increased significantly in these years, resulting in a challenging period for the transport sector. The EU Commission is facing the energetic transition adopting the resolution “Fit for 55”, which mandates a 55% reduction by 2030 of the Green House Gases (GHG) emissions (compared to 1990), moving towards Carbon Neutrality by 2050. To meet these targets, in addition to battery electric vehicles, hydrogen represents a fundamental pillar in the transportation, both for Fuel Cells and Internal Combustion Engines. Hydrogen Internal Combustion Engine (H2 ICE) constitutes one of the best technologies due to its zero CO2 tailpipe emissions and its minimal criteria pollutant: extremely low HC, CO and PM engine-out emissions coming only from lubricant oil consumption and low NOx stemming from lean combustion.