Ovarian cancer accounts for 3.3% of all cancers in women worldwide but it is responsible for approximately half of the deaths related to gynecological cancer. The low survival rate is primarily due to the difficulty in diagnosing this neoplasm at early stages, and this occurs because early ovarian cancer is usually asymptomatic. Moreover, an adequate discrimination between benign and malignant lesions is a key point for a correct management of the patient. Ultrasound is the most used method for assessment of adnexal lesions due to its non-invasiveness, low cost and widely diffusion. Specifically, Color Doppler and Power Doppler imaging techniques are used to differentiate between benign and malignant tumors by evaluating the vascularization within the adnexal mass.