The use of High Performance Computing (HPC) in three-dimensional Computational Fluid Dynamics (3D-CFD) was identified as one of the main source of the evolution of the sector, and it was identified that, in the current CFD market, both open source software and license-based commercial software are developing advanced HPC integrations, such as parallel computation and cloud computing. Open-source and license-based software both have advantages and disadvantages related to software costs, different user experience and reliability. The objective of this thesis work is to reproduce some case studies using both types of tools, in order to compare them to a benchmark obtained in a well-established commercial CFD software.