Deep Brain Stimulation of the SubThalamic Nucleus (STN-DBS) has been proven successful in alleviating symptoms and improving the quality of life in patients suffering from Parkinson’s Disease (PD). It involves the implantation of a stimulating electrode within the STN and its accurate placement is essential for achieving optimal therapeutic outcomes. To this aim, MicroElectrode Recordings (MERs) are acquired during the surgery to provide real-time visual and auditory confirmation of the electrode position. The objectives of this thesis focus on improving the accuracy of STN targeting and gaining deeper insight into MER properties. For these purposes, a dataset of MERs from 36 PD patients, who underwent bilateral DBS electrode implantation, is retrospectively analyzed.