In the context of the urban regeneration in Guangzhou, the old city has become an important area to improve the urban environment and the appearance. The existing urban regeneration design methods, such as the rapid regeneration of large-scale demolition and construction, the small-scale regeneration without unified planning, and the acupuncture regeneration that needs to be analyzed in combination with the actual situation, are not applicable to the old city of Guangzhou today; Therefore, Guangzhou's old city regeneration needs to be supplemented with a new approach, which can not only ensure the applicability to a series of spacial problems, but also maintain the previous regeneration strategy to adopt precise methods in the face of specific projects, while have a certain degree of sustainability.