The aim of thermal therapies in cancer treatment is to significantly alter the temperature of the target (tumor) region without damaging the healthy tissues. Microwave hyperthermia (HT) consists in heating locally the region of interest up to 42-44°C by means of an antenna applicator, while keeping the heat in the surrounding area at a tolerable level for the tissues and therefore for the patient himself. Hyperthermia is used in association with conventional cancer therapies, being able to sensitize tumors to radiotherapy and chemotherapy (cancer therapies are more effective at the same dose) without adding toxicity. In order to improve the clinical outcome of hyperthermia treatments, a patient-specific treatment planning is needed, where a numerical model of the patient is created, the baseline thermal and dielectric parameters (i.e., the values found in the Literature) are assigned to the different tissues, the antenna feedings are optimized using an EM simulation solver, and the corresponding temperature map is obtained by solving the bioheat equation.