Current environmental situation requires reduction of all human activities that have heavy impacts on our planet. A considerable part of pollution comes from transportation, that produces about one fourth of total carbon dioxide, main source of greenhouse effect. This condition has required to switch vehicles fuels toward cleaner options as natural gas, electricity and hydrogen. This paper aims to analyze which are the impacts of alternative fuel vehicles on the production process by examining four versions of a semi-truck. IVECO S-Way in its native diesel and optional natural gas versions have been modified in a joint venture effort with NIKOLAMotor Company in order to become a Battery Electric Vehicle and Fuel Cell Electric Vehicle.