In recent years, global sustainability challenges, such as world population growth and over-consumption of non-renewable resources, are pushing societies to establish and follow circular and regenerative approaches. Bioeconomy and circular economy can help to alleviate environmental problems caused by the lack of modern and smart waste management systems, which do not provide operational transparency, traceability, security and trusted data provenance features. In fact, today’s technologies leveraged for waste management, strictly relies on manual and centralized silos making them vulnerable and the single point of failure of the entire system. To meet the challenge, the transition plan must consider the necessity to integrate economic and environmental perspectives as well as stimulating social awareness and dialogue, leading to more conscious behaviors.