The rising in importance of minimally invasive surgical techniques goes unfortunately side by side with the increasing number of cancer cases worldwide, especially in poor countries. The fact that not every healthcare system can guarantee proper cures to all the citizens underline the importance of research in finding always cheaper protocols. Laser ablation is a new frontier that could open access to curing cancer also for those that nowadays cannot afford other treatments for the high cost of hospitalisation and therapies as well. Cancer is a pathological condition where the proliferation of cells in organs and tissues modifies the normal functioning and structure; for this reason any typology of mini-invasive surgical treatment, either hyper-thermal or hypothermal, has the aim of forcing cells' necrosis.