Parkinson’s disease (PD) is a gradual neurodegenerative disorder defined by the loss of dopaminergic neurons and the presence of Lewy bodies in the basal ganglia area. The main manifestations of PD are motor symptoms, such as bradykinesia (i.e., slowness of movement), tremor, rigidity and balance instability, nonetheless nonmotor symptoms, as sleep disorders and dementia, are common too. Levodopa is the gold standard medication; its effectiveness is remarkable at the beginning, but it decreases with the progress of the therapy. Besides, motor complications appear as side-effects of the medication causing dyskinesia (i.e., involuntary movement) and motor fluctuations. To reduce the medication drawbacks and optimize the doses of levodopa, periodical assessments at the hospital are necessary.