The field of the robotic prosthesis didn’t progress for decades after its debut in the 60’s, mainly because of the limits related to the kind of electrodes used and the lack of sensory feedback. This framework and the recent invention of an innovative technique for integrating the prosthesis inside the bones of a patient led to the creation of a very promising European project renamed DeTOP. Its main purpose is to develop a groundbreaking robotic prosthesis controlled by implanted electrodes and able to offer sensory feedback to the patient. Thanks to its longstanding expertise in electronics, the CSEM contributed to this project through the development of a state of the art System on Chip able to sense the electric signals collected by the implanted electrodes and generated by the muscular contraction for controlling the robotic hand in a power-efficient way.