Large enterprises operate in contexts marked by structural complexity, interdependencies, and constant change. Within such environments, traditional Project Management approaches may encounter limitations in delivering the responsiveness and effective coordination required at the organizational level. Consequently, Agile Project Management has emerged as more suitable approach for dealing with uncertainty and promoting adaptive organizational processes. While Agile practices are established at the team level, their implementation across large enterprises introduces a wider set of challenges. When extended beyond individual teams, these practices interact with broader organizational dynamics that make their application more elaborate. Coordinating work across multiple units, aligning different ways of operating, and ensuring consistency throughout the enterprise become increasingly demanding, hindering the realization of the intended benefits of Agile approaches.