The field-coupled nanocomputing (FCN) is one of the most interesting beyond-CMOS technologies, in particular, its molecular implementation (molFCN) takes advantage of its intrinsic features: nanometric dimensions and low power requirement. With each passing year, it becomes increasingly important in electronics due to the slowdown in the scaling of traditional electronics. Until today, in the scientific literature, no integrated systems with molFCN and CMOS have been proposed. This thesis investigates the possibility of interfacing the CMOS technology with the FCN one. Three solutions have been thought of, which exploit different physical phenomena: capacitive coupling, photons scattering, and energy levels alteration. The system designed in this thesis is the molecular junction-based one.