This Master's Thesis project deals with the effects of electrical stimulation provided to pre-osteoblasts through nanofibers. While electric fields are known to influence a variety of cell activities, nanostructures can mimic the biological environment structurally. Therefore, one way to improve the functional outcome of bone tissue engineering may be electrical stimulation in combination with a biomimetic structure (e.g. nanofibers). The goal of this project is the analysis the properties of electrical stimuli delivered through a nanostructure (for example, the confinement of the field in a sub-cellular region), with a finite element method (FEM) approach, followed by the synthesis of the conductive nanofibers and cell culture experiments.