Why do human joints wear out during aging or better how do joints resist wear over a lifetime? Synovial joints of the human body are complex living biological and mechanical system consisting of articular cartilage, bone, menisci, ligaments and synovium that allow movement so that friction and wear are minimal.The success of many implant or medical instruments depends on the biomaterial used. Synthetic materials like metals, polymers, ceramics and composite have had an important role to several medical devices. Nowadays the life of an implant is about 15 years and consequently, a reduction in wear and friction of medical devices and the development of the design is becoming the core of several studies.