Drugs are used to improve the health and the quality of life of patients suffering particular diseases. Medication can be consumed in several ways, although not all of them are suitable for each type of drug. Recently, new methods of delivering drugs through the skin have been investigated, in order to overcome the obstacles shown by traditional methods.Microneedle (MN) technology has become an effective alternative to the traditional delivery strategies and it has made an important contribution to medical practice. MNs are shown to be successfully able to pierce the outermost skin layer, being minimally invasive and less painful compared to a conventional hypodermic needle.