Martina Angotti
A Unified Finite Element and Electrical Circuit Framework for 0D-1D Vascular Hemodynamics: Application to Coronary Bypass Graft Networks.
Rel. Claudio Chiastra. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2026
Abstract
Coronary artery disease (CAD) is one of the leading causes of morbidity and mortality worldwide, arising from the progressive narrowing of the coronary arteries due to atherosclerotic plaque formation. Coronary artery bypass graft (CABG) surgery is a well-established revascularization procedure that restores blood flow to the myocardium by bypassing occluded arterial segments. Despite its clinical efficacy, long-term graft patency remains a significant concern, as both early and late graft failure can compromise patient outcomes. Understanding the hemodynamic conditions that predispose grafts to occlusion or remodelling is therefore of considerable clinical importance, motivating the use of computational tools to investigate blood flow in pre- and post-operative CABG anatomies.
Three-dimensional Computational Fluid Dynamics (CFD) can resolve hemodynamics within complex anatomical geometries with high spatial fidelity, but its prohibitive computational cost has historically motivated the development of reduced-order models
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