This master’s thesis is conducted within the framework of a broader European research initiative, the Dorian Gray project, exploring the correlation between Mild Cognitive Impairment (MCI) and Cardiovascular Diseases (CVDs). The European project adopts a multidomain approach that combines MCI risk monitoring with physical exercise and cognitive training. Recent studies have highlighted the role of CVD symptoms in damaging brain structures and its vascular network, thus suggesting that these may act as risk factors in the onset of dementia. Physical inactivity in the ageing population should be addressed as a key variable: it can double the risk of developing dementia later in life if not accounted for.