Against the broader backdrop of revitalization and renewal, the transformation of historical and cultural districts is undergoing a cognitive shift from the binary opposition between preservation and development to a more integrated approach. Traditional top-down planning and design methods face inherent limitations in balancing heritage conservation with dynamic revitalization. The challenges encountered in recent years during Guangzhou's revitalization practices highlight the urgency of adopting more refined, diversified, and culturally integrated design strategies. Emerging in recent years, Tactical Urbanism, as a bottom-up, small-scale renewal approach, offers new perspectives for addressing these challenges. This study takes the Guangfunan Historical and Cultural District in Guangzhou as a case to systematically explore the adaptive strategies and practical pathways of Tactical Urbanism in the renewal of historic districts.