Duchenne muscular dystrophy (DMD) is a genetic disorder characterized by progressive degeneration of muscular tissue, caused by mutations in the dystrophin gene. It primarily affects males and leads to an average life expectancy of twenty years. Currently, there is no cure for DMD, but there are different treatments that attempt to improve quality of life and delay the disease’s progression. The research is focusing on other strategies involving gene therapy as a potential cure for the disease. While these approaches are giving encouraging results, in the clinical trials they are not as effective as expected: the inflammation and associated defects in the muscles complicate their regeneration.