Quantitatively assessing cardiomyocyte contractility, combined with electrophysiological measures, is essential for understanding cardiac functionality, cardiovascular diseases, and pharmacological responses. Specifically, drugs interacting with ion channels can impair heart function, affecting both mechanical contraction and electrical activity. This thesis proposes an innovative approach to simultaneously monitor these aspects by integrating non-invasive optical and electrophysiological techniques. For the analyses conducted, the signals were extracted from cardiomyocytes derived from induced pluripotent stem cells (iPSC-CMs), which are somatic cells that can be reprogrammed returning to a pluripotent state resembling embryonic stem cells. By employing the Farneback dense optical flow method to analyze videos acquired with a microscope and a camera, the cellular motion can be tracked.