Domenico Falbo
Vorticity-based analysis in computational hemodynamics models of carotid bifurcation pre and post carotid endarterectomy.
Rel. Valentina Mazzi, Umberto Morbiducci, Diego Gallo, Karol Calo'. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2024
Abstract
Atherosclerosis is one of the most diffuse pathological conditions of the arterial system. It is characterized by the thickening, hardening, and loss of elasticity of arterial walls, which restricts blood flow. This occurs as cholesterol, fats, and cellular debris accumulate between the intima and media layers of the artery wall, forming plaques. Carotid bifurcations are a common site for the development of atherosclerotic plaques. The constriction of the carotid artery results in the reduction of blood flow, which, in the worst case, could lead to a stroke. The most used surgical procedure to remove atherosclerotic plaques in carotid bifurcations is carotid endarterectomy (CEA).
Restenosis after CEA is an important complication affecting patients' outcomes, leading to the development of cerebral symptoms or even carotid occlusion and stroke
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