Nowadays, the automotive sector is going through a phase of continuous evolution, driven by technological innovation and new requirements for sustainable mobility. In this context, the issue of door-to-door delivery management is assuming an increasingly important role, due to the expansion of e-commerce. This thesis work is part of a project in collaboration with a major car manufacturer, which aims to develop a last-mile delivery vehicle with a modern and sustainable design. The commercial vehicle in question will feature an innovative, modular structure and an optimized arrangement of packages inside it. The vehicle will be powered by a battery propulsion system and could feature autonomous driving technology, to improve the efficiency and sustainability of delivery operations.