The impact of climate change on agriculture represents a crucial challenge for food and water security in the coming decades. In this context, seasonal forecasts are an essential tool for adaptation in the agricultural sector, offering valuable information for medium-term decision-making. This study, therefore, aims to analyze the uncertainty and to assess the consistency of seasonal forecasts of meteorological variables such as maximum temperature, minimum temperature, and precipitation in the Po River Basin, with a particular focus on the Pianura Padana area, where the agricultural production is concentrated. Moreover, the seasonal forecasts of irrigation requirements of maize in the area of interest will be estimated to assess the propagation of uncertainty to dependent variables.