Software companies that develop and distribute any application need to constantly face the challenge of an adversary manipulating it to alter its behavior, stealing intellectual property such as proprietary algorithms and distributing illegal copies. In order to limit the economic losses caused by such malicious activities, various protection techniques were invented to increase the time and cost required by the attackers to succeed. The first line of defense is given by obfuscation techniques, that aim to make reverse engineering the code difficult, at the expense of execution performance. Given the high amount of existing techniques and the challenge of evaluating protection strength and performance overhead, finding the best tradeoff between these two objectives is a complex process.