Binders play a crucial role in ensuring the structural stability and efficient transport of reactants and products at the catalyst surface in Proton-Exchange Membrane (PEM) electrolyzers. This study presents a comprehensive comparative analysis of an innovative material, s-PIM (sulfur-containing Polymer of Intrinsic Microporosity), as a polymeric binder in PEM electrolyzers. The research focuses on investigating the advantages/disadvantages of using s-PIM instead of the traditional Nafion binder, with a specific emphasis on assessing the electrochemical performance of the electrodes. The research started with a screening of s-PIM as a binder at the cathode and anode within a three-electrode cell. Linear sweep voltammetry (LSV) and chronoamperometry (CA) were employed to analyze the electrocatalytic activity and stability over time.