This thesis explores the feasibility and economic viability of various hydrogen refueling station layouts across two distinct urban settings, Torino and Palermo. Six scenarios were meticulously designed and analyzed, with a focus on sustainability, cost-effectiveness, and risk assessment. The three layout options considered for each city were: 1.??On-grid refueling station with integrated photovoltaic (PV) panels. 2.??Off-grid refueling station with PV panels and a lithium-ion battery storage system. 3.??Hybrid off-grid refueling station with PV panels and a hydrogen fuel cell to produce electricity from hydrogen. All the scenarios were designed and analyzed through the software HOMER Pro, which optimizes micro-grid designs across all industries to minimize the costs and to calculate important economic indexes such as the Levelized Cost of Hydrogen (LCOH) and Levelized Cost of Energy (LCOE) to compare the various layouts to each other.