Designing wind turbine blades for offshore applications presents significant structural challenges due to their flexibility and exposure to varying loads. However, the existing literature often overlooks the impact of fatigue on the blade composites. This study aims to investigate the influence of blade flexibility on multiaxial fatigue analysis for offshore wind turbine applications. To achieve this objective, a comprehensive analysis of the IEA 3.4 MW reference wind turbine is performed, considering both fixed and floating configurations. First, an overview of offshore wind energy and fatigue theory is conducted. Then, an aeroelastic analysis of the wind turbine blade, incorporating realistic environmental load simulations, is developed.