Since the first launch in 2003, CubeSats raised in importance on the low-cost mission’s panorama. Widely used to date, not only by universities but also by agencies, due to their versatility and ever-increasing deployment possibilities. This is the context of the ESA Space Riders mission. Space Rider is the first European reusable transportation system, an uncrewed robotic laboratory. After launch on Vega-C, it will stay in low orbit for about two months. Experiments inside its cargo bay will allow benefice research in various scientific fields as well as the possibility to demonstrate and validate technologies for different applications, such as robotics, Earth observation, telecommunication, and Surveillance.