The disease named Multiple Sclerosis (MS) is characterized by an autoimmune response resulting in the progressive degeneration of nerve cells. Their ability to transmit electrical signals becomes impaired, leading to disruptions in communication between components within the Central Nervous System (CNS). The manifestation and severity of MS symptoms exhibit substantial heterogeneity across individuals. Notably, the impairments in motor functions and cognitive abilities impact significantly on daily activities. As a result, prioritizing rehabilitation is crucial for effectively managing MS and improving the well-being of individuals living with the condition. The purpose of this thesis is to develop a Mixed Reality system for the rehabilitation of cognitive and motor functions through activities involving the upper limb.