Electric fields (EFs) have a considerable influence in cell functions producing a wide selection of biological effects. Various combinations of EF frequency and intensity triggers different responses. EF may alter functionality and permeability of cell membrane, resulting in a higher flow of ions leading to membrane depolarization and intracellular calcium increase concentration, both features that could trigger apoptosis. This effects have been studied for decades achieving promising results in cancer treatment. The present work aims on the investigations of two different applications of EFs: a new promising therapy for cancer treatment using low-intensity (1--3 V/cm) alternating EFs with intermediate frequencies (100--500 kHz), named {Tumour-Treating Fields} (TTFields), observing delay in both mitosis and cytokinesis phases of the cell cycle and disrupting effects on the formation of the mitotic spindle during cell division leading to possible cell death.