Synaptic plasticity is thought to be the main process underlining how we learn, store memories, and even recover from injuries. With this term, we refer to the ability of the brain to change the strength of its synaptic connections in response to stimuli: an increase in the synaptic transmission is called potentiation, while a decrease results in what is named depression. One particular form of synaptic plasticity, called spike-timing dependent plasticity (STDP), emphasizes the temporal order and time interval between the presynaptic and postsynaptic potentials. In order to study the complex phenomena entailing neural plasticity, intracellular techniques for recording and stimulation have been extensively used.