Today’s challenges, such as climate change, population growth, urbanization and increasing demand of resources, are a potential wake-up call that we can no longer ignore. On these issues, the construction industry plays a focal role and should activate strategic solutions to improve its impact on the environment. One solution could consist to the transition to a circular economy model for the entire construction life cycle, through the help of innovative models and technologies. Environmental standards and voluntary protocols provide tools for improving structure’s impact but lack a methodology for making the construction phase circular and sustainable. From the design phase of a new work, it becomes fundamental to make the right choices in terms of materials, energy and water and to plan efficiently for its realization.