The thesis explores the territory of the river Scheldt in Northern Europe and the spatial relations within its water basin and network. Through an articulated survey rooted in genealogical, socio-economic, and political aspects, the research shows that the very existence of the river Scheldt has been determined by the relation with other subjects, mainly humans, through their existence and actions. In fact, we are dealing with an economic corridor and a freshwater supplier for crops, that has been subjected to so many transformation that is impossible to recognize its physiological behavior. In a way, the river can not be defined as a "natural" element but a hybrid system of interactions or even a machine.