Rossella Todaro
In silico mechanical characterization of a new corneal implant for the treatment of keratoconus.
Rel. Diego Gallo, Claudio Chiastra, Dario Carbonaro. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2022
Abstract
The work presented in this thesis is the result of a collaboration between the start-up Recornea and Politecnico di Torino. The project aims to develop, validate clinically, and commercialize a new corneal implant for the restoration of the physiological shape of corneas affected by keratoconus (KC) and, above all, study its mechanical characterization. This disease involves the progressive irregular thinning and gradual bulging of the cornea into a conical shape, leading to detrimental refractive defects, including astigmatism, myopia, and a poor quality of life for keratoconus patients. Currently, the main treatments for corneal ectasia vary according to the structural changes of the cornea, the stage of KC, and the refractive error of the patient.
These treatments range from non-invasive options capable of providing short-term and palliative results to invasive techniques for more long-term outcomes
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