As a revolutionary means of transport in the transportation industry, the successful operation of high-speed railways has not only changed the transportation landscape and ushered in a new era of transportation but has also profoundly affected the economic development of cities along high-speed railways, generating a huge economic effect. As the scale of high-speed railways in Shaanxi Province continues to expand rapidly, there is a great need to scientifically study the impact of high-speed railways on the economic development of cities along the lines and to avoid the negative impact brought by high-speed railways, there is an urgent need for the regions along the lines to formulate reasonable industrial development strategies to guide the scientific development and reasonable layout of industries.