In 2019, 503.790 accidents in the industry sector have been recorded in Italy, 974 of which involved death. Among the causes of accidents there are environmental causes: accidents happen because of the working environment and the triggering factors can include poor lighting, ambient temperature, air pollution, sound pollution. More recently, indoor air quality, particularly when concerning CO2 and Particulate matter, emerged as one of the most reliable proxies indicating the probability of viral infection transmission. This thesis presents the “SALVO” project, designed and developed with ENEA (Italian National Agency for New Technologies and Sustainable Development) and STMicroelectronics, that using IoT and Cloud Computing, aims at creating a distributed environment monitoring platform to improve workers’ security in an Industry 4.0 context.