Living beings interact with the external environment through specific receptors, collecting different information and processing appropriate responses. As a matter of fact, damage to information transmission and control mechanisms, due to neuropathy, stroke, or Parkinson's disease, can cause both motor and sensory disturbances. Since the foot is the first and the only direct contact between the human body and the outside world, interest in the role of sensory feedback, generated by the stimulation of mechano-receptors, in the regulation of motor activity and step kinematics, is constantly increasing. The application of mechanical stimuli, as to avoid them from causing resonance in the patient, produces greater coordination of synergistic muscles, an increase in the motor units recruited, and improves the vibratory perception threshold (VPT).