Quantum computing is one of the main concerns of information security in recent years, due to its capability of breaking in polynomial time asymmetric algorithms, that are the foundation of the most used security protocols. Quantum Key Distribution (QKD) is a promising approach to mitigate the issue which leverages the quantum physics phenomena to introduce cryptographic information-theoretical secure key exchanges even in the presence of powerful quantum computers, but its adoption is still at the early stage and a lot of works focused on the physical aspects and devices instead of the implementation issues. Today's infrastructures are shifting to distributed scenarios where servers are hosted in data centers often shared among several customers and spread over different locations; cloud computing is becoming a fundamental block in the deployment of applications and hence cryptographic protocols of the future must be compatible with these architectures.