Given the risks associated with liver transplant operations and the protagonist role of paracetamol overdose in cases of hepatotoxicity, there's a growing need for a fast, cheap and easy to use method for its detection. Compared to traditional methods like HPLC, spectrophotometry, colourimetry and chemiluminescence, electrochemical sensors have the potential of reaching less fortunate hospitals that cannot afford expensive equipment and serve as a quick point-of-care screening method for suspected cases of paracetamol toxicity. Moreover in the field of therapeutic drug monitoring a lot of effort has been put in developing electrochemical sensors to better control the depth of anesthesia, where paracetamol is usually a component.