Cancer relapse is a leading cause of death nowadays, which brings related health and financial costs. The XtraUS European project, in which this Master Thesis is inserted, aims at developing a device to treat circulating cancer cells in the bloodstream responsible of tumour recurrence. The core idea is the application of an extracorporeal blood circulation technology in which the combination of a stimulus with responsive and targeted nanoconstructs can lead to toxic species able to kill circulating tumour cells. The aim of the work is the study of this energetic stimulation on nanoconstructs and its consequences, in different static experimental set-up, in order to test an already approved device, but also move to other possible arrangements for the future development of a cartridge for blood treatment.