Nowadays, the framework of renewable energy sources is highly dynamic and constantly evolving, the urgent need of cutting CO2 emissions is pushing humankind to find drastic alternatives to what was the energy paradigm merely a decade ago. In order to be effective for our health, this major shift needs a comprehensive and coordinated set of actions, ranging from a more rational use of the already existent form of energy, passing through the impactful penetration of renewables and alternative energy vectors (e.g. hydrogen-based technologies), to the work on systems’ interoperability, in the attempt of taking out their full potential. Another crucial aspect is the worldwide access to energy.