Acoustic loads are one of the major concern in the structural design of SpaceCrafts (SCs). They are mostly caused by the launcher fairing sound pressure level during lift-off and ascending phase. In this work a number of acoustic assessments have been performed by using MSC Actran SW and by referring to a real S/C structure and a real launch acoustic environment. Three types of acoustic analysis are available in MSC Actran for the purpose: 1)??Modal frequency analysis, 2)??Direct frequency analysis 3)??Virtual SEA analysis. Each one of these three analysis implies different assumptions and different computational effort, which may be noteworthy. Moreover, a significant number of parameters have to be carefully chosen by the analyst in order to finalize the each analysis run.