Recent advancements in electronics and microfabrication techniques have increased attention to the use of implantable miniaturized biosensors. In vivo biosensing is going to radically change healthcare by allowing personalized medicine. By continuous monitoring, the basic health of an individual could be well understood, making possible to detect upcoming pathologies. A further option is the continuous monitoring of a therapeutic drug that could eliminate dosage intakes by providing an individualized pharmacokinetic report of a drug. These devices could also be used in vitro to monitor cell cultures that are useful for various purposes, such as understanding and modelling certain biomechanisms, developing novel medicinal products and treatments or in the area of regenerative medicine.