The blood flowing in the cardiovascular system allows the transport of nutrients to cells and the removal of metabolites and toxins. Among substances carried by the blood, oxygen is one of the most relevant due to its key role in all metabolic processes. Insufficient delivery of oxygen to cells leads to hypoxia and consequent disfunction and disorganization of cells. If this condition occurs in arterial walls, it is considered to promote the origination and development of atherosclerotic lesions. Therefore, studying mechanisms that rule oxygen transport in blood may allow to localize regions of arterial wall with a non-negligible probability to develop atherosclerosis.