Clelia Venezia
Exploring Helical Flow Topology in Coronary Arteries through a Complex Networks-Based Approach.
Rel. Umberto Morbiducci, Diego Gallo. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2019
Abstract
The role of hemodynamics in vascular physiopathology has been widely elucidated through the increasingly detailed modeling of cardiovascular flow. In recent studies, the beneficial role of helical flow in the onset of cardiovascular diseases and its physiological significance was verified. However, the spatiotemporal evolution of spiral blood flow and its level of organization in dynamically correlated structures were not largely examined. The proposed study aims to bridge this gap applying the complex networks (CNs) theory to ten swine-specific hemodynamic models of left anterior descending (LAD) coronary artery. The complexity of arterial flow was schematized through nodes and links and studied applying the characteristic CNs metrics.
Starting from available computational fluid dynamics (CFD) data, correlations between the nodal time-histories, defined in the grid points of the CFD volume mesh, of the bulk flow descriptor kinetic helicity density (Hk), were computed
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