Riccardo Di Dio
Analyzing movement patterns to facilitate the titration of medications in late stage Parkinson's disease.
Rel. Danilo Demarchi. Politecnico di Torino, Corso di laurea magistrale in Ingegneria Biomedica, 2019
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Abstract
Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer. Nowadays more than 10 million people worldwide are affected and this number is increasing at a rate of 60 thousands new diagnoses per year in US only. It has an impact on the US healthcare industry of 23 billion dollars per year represented by direct and indirect costs. Periodically quantify the severity of the symptoms is important to arrange the medication doses and schedule the intake times to avoid or keep at minimum the side effects of the medications and keeping always a low level of impairment caused by the symptoms.
This is a problem of drug titration, typical of those drugs that have a wearing off effect, like Levodopa, used for Parkinson's Disease
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