This work has the aim to study the feasibility on a commercial scale, technical and economical, of the introduction of SOFC-based cogeneration systems to supply Hospitals with electricity and heat. Countries that have market with greatest potential are analysed, in USA and European areas. First part of this analysis focuses on a deep literature review, to define how many hospitals are distributed over the countries, and to describe the related energy consumption, analysing the daily profile and the energy intensity. Then, a techno-economic model is built to calculate the impact, over a period of 15 years, of the installation of SOFC system, based on the available data on the market and in literature.